A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration
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Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration.
Alternative splicing of nucleoredoxin-like 1 (Nxnl1) results in 2 isoforms of the rod-derived cone viability factor. The truncated form (RdCVF) is a thioredoxin-like protein secreted by rods that promotes cone survival, while the full-length isoform (RdCVFL), which contains a thioredoxin fold, is involved in oxidative signaling and protection against hyperoxia. Here, we evaluated the effects of...
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15 صفحه اولUpregulation of pro-inflammatory genes accompanies photoreceptors demise in canine models of retinal degeneration
These abstracts are licensed under a Creative Commons Attribution-NonCommercial-No Derivatives 4.0 International License. Go to http://iovs.arvojournals.org/ to access the versions of record. 378 Cellular mechanisms of retinal diseases and ocular therapeutics Tuesday, May 09, 2017 3:45 PM–5:30 PM Exhibit/Poster Hall Poster Session Program #/Board # Range: 3587–3601/B0146–B0160 Organizing Sectio...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2019
ISSN: 1422-0067
DOI: 10.3390/ijms20194807